Current topics:
cdc2/cyclin B activation; plasma membrane repair
Modeling of cdc2/cyclin B activation: simulations
Cyclin B localization and dynamics during meiotic maturation
Electrophysiology of wound healing
Plasma membrane wound healing (movies)
Past work:
A new model for
nuclear envelope breakdown (publication)
Nuclear
envelope breakdown (movie)
Selective destruction
by multiphoton excitation
Association of Ran with chromosomes
Exocytosis in sea urchin eggs (movies)
Slow Axonal
Transport (movie)
Actin filament translocations
in sea urchin eggs (movie)
Calcium in cilia (movie with sound)
Video essay for
Molecular Biology of the Cell: Imaging echinoderm fertilization
Sea urchin fertilization: simultaneous phase contrast and calcium
Endoplasmic Reticulum:
ER reorganization during Xenopus oocyte maturation (publication)
ER
and Golgi during mitosis (figures
and movies)
ER in mouse oocytes (pictures)
ER during maturation
and fertilization using GFP-KDEL
--Starfish oocytes (movie)
--GFP-KDEL (info)
ER in purkinje
neurons
ER
in sea urchin eggs - labeling by DiI, and change at fertilization
Cortical ER
in sea urchin eggs
ER in Fibroblasts:
Coupling of ER with retrograde cortical movements in fibroblasts
(movie)
Labeling by DiOC6(3) (images)
Double labeling
by DiOC6(3) and BiP (images)
Microtubules and the
ER (images)
Collaborations:
Phospholipase C gamma in fertilization (JCB
full text)
GFP labeling of the Golgi apparatus (movies)